diff --git a/crypto/Kconfig b/crypto/Kconfig
index 285f82647d2b7..c6c71acf7d56e 100644
--- a/crypto/Kconfig
+++ b/crypto/Kconfig
@@ -290,6 +290,7 @@ config CRYPTO_CURVE25519
 config CRYPTO_CURVE25519_X86
 	tristate "x86_64 accelerated Curve25519 scalar multiplication library"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_LIB_CURVE25519_GENERIC
 	select CRYPTO_ARCH_HAVE_LIB_CURVE25519
 
@@ -338,11 +339,13 @@ config CRYPTO_AEGIS128
 config CRYPTO_AEGIS128_SIMD
 	bool "Support SIMD acceleration for AEGIS-128"
 	depends on CRYPTO_AEGIS128 && ((ARM || ARM64) && KERNEL_MODE_NEON)
+	depends on !KMSAN # avoid false positives from assembly
 	default y
 
 config CRYPTO_AEGIS128_AESNI_SSE2
 	tristate "AEGIS-128 AEAD algorithm (x86_64 AESNI+SSE2 implementation)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_AEAD
 	select CRYPTO_SIMD
 	help
@@ -478,6 +481,7 @@ config CRYPTO_NHPOLY1305
 config CRYPTO_NHPOLY1305_SSE2
 	tristate "NHPoly1305 hash function (x86_64 SSE2 implementation)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_NHPOLY1305
 	help
 	  SSE2 optimized implementation of the hash function used by the
@@ -486,6 +490,7 @@ config CRYPTO_NHPOLY1305_SSE2
 config CRYPTO_NHPOLY1305_AVX2
 	tristate "NHPoly1305 hash function (x86_64 AVX2 implementation)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_NHPOLY1305
 	help
 	  AVX2 optimized implementation of the hash function used by the
@@ -599,6 +604,7 @@ config CRYPTO_CRC32C
 config CRYPTO_CRC32C_INTEL
 	tristate "CRC32c INTEL hardware acceleration"
 	depends on X86
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_HASH
 	help
 	  In Intel processor with SSE4.2 supported, the processor will
@@ -639,6 +645,7 @@ config CRYPTO_CRC32
 config CRYPTO_CRC32_PCLMUL
 	tristate "CRC32 PCLMULQDQ hardware acceleration"
 	depends on X86
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_HASH
 	select CRC32
 	help
@@ -704,6 +711,7 @@ config CRYPTO_BLAKE2S
 config CRYPTO_BLAKE2S_X86
 	tristate "BLAKE2s digest algorithm (x86 accelerated version)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_LIB_BLAKE2S_GENERIC
 	select CRYPTO_ARCH_HAVE_LIB_BLAKE2S
 
@@ -718,6 +726,7 @@ config CRYPTO_CRCT10DIF
 config CRYPTO_CRCT10DIF_PCLMUL
 	tristate "CRCT10DIF PCLMULQDQ hardware acceleration"
 	depends on X86 && 64BIT && CRC_T10DIF
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_HASH
 	help
 	  For x86_64 processors with SSE4.2 and PCLMULQDQ supported,
@@ -765,6 +774,7 @@ config CRYPTO_POLY1305
 config CRYPTO_POLY1305_X86_64
 	tristate "Poly1305 authenticator algorithm (x86_64/SSE2/AVX2)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_LIB_POLY1305_GENERIC
 	select CRYPTO_ARCH_HAVE_LIB_POLY1305
 	help
@@ -853,6 +863,7 @@ config CRYPTO_SHA1
 config CRYPTO_SHA1_SSSE3
 	tristate "SHA1 digest algorithm (SSSE3/AVX/AVX2/SHA-NI)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SHA1
 	select CRYPTO_HASH
 	help
@@ -864,6 +875,7 @@ config CRYPTO_SHA1_SSSE3
 config CRYPTO_SHA256_SSSE3
 	tristate "SHA256 digest algorithm (SSSE3/AVX/AVX2/SHA-NI)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SHA256
 	select CRYPTO_HASH
 	help
@@ -876,6 +888,7 @@ config CRYPTO_SHA256_SSSE3
 config CRYPTO_SHA512_SSSE3
 	tristate "SHA512 digest algorithm (SSSE3/AVX/AVX2)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SHA512
 	select CRYPTO_HASH
 	help
@@ -1034,6 +1047,7 @@ config CRYPTO_WP512
 config CRYPTO_GHASH_CLMUL_NI_INTEL
 	tristate "GHASH hash function (CLMUL-NI accelerated)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_CRYPTD
 	help
 	  This is the x86_64 CLMUL-NI accelerated implementation of
@@ -1084,6 +1098,7 @@ config CRYPTO_AES_TI
 config CRYPTO_AES_NI_INTEL
 	tristate "AES cipher algorithms (AES-NI)"
 	depends on X86
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_AEAD
 	select CRYPTO_LIB_AES
 	select CRYPTO_ALGAPI
@@ -1208,6 +1223,7 @@ config CRYPTO_BLOWFISH_COMMON
 config CRYPTO_BLOWFISH_X86_64
 	tristate "Blowfish cipher algorithm (x86_64)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_BLOWFISH_COMMON
 	imply CRYPTO_CTR
@@ -1238,6 +1254,7 @@ config CRYPTO_CAMELLIA
 config CRYPTO_CAMELLIA_X86_64
 	tristate "Camellia cipher algorithm (x86_64)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	imply CRYPTO_CTR
 	help
@@ -1254,6 +1271,7 @@ config CRYPTO_CAMELLIA_X86_64
 config CRYPTO_CAMELLIA_AESNI_AVX_X86_64
 	tristate "Camellia cipher algorithm (x86_64/AES-NI/AVX)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_CAMELLIA_X86_64
 	select CRYPTO_SIMD
@@ -1272,6 +1290,7 @@ config CRYPTO_CAMELLIA_AESNI_AVX_X86_64
 config CRYPTO_CAMELLIA_AESNI_AVX2_X86_64
 	tristate "Camellia cipher algorithm (x86_64/AES-NI/AVX2)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_CAMELLIA_AESNI_AVX_X86_64
 	help
 	  Camellia cipher algorithm module (x86_64/AES-NI/AVX2).
@@ -1317,6 +1336,7 @@ config CRYPTO_CAST5
 config CRYPTO_CAST5_AVX_X86_64
 	tristate "CAST5 (CAST-128) cipher algorithm (x86_64/AVX)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_CAST5
 	select CRYPTO_CAST_COMMON
@@ -1340,6 +1360,7 @@ config CRYPTO_CAST6
 config CRYPTO_CAST6_AVX_X86_64
 	tristate "CAST6 (CAST-256) cipher algorithm (x86_64/AVX)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_CAST6
 	select CRYPTO_CAST_COMMON
@@ -1373,6 +1394,7 @@ config CRYPTO_DES_SPARC64
 config CRYPTO_DES3_EDE_X86_64
 	tristate "Triple DES EDE cipher algorithm (x86-64)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_LIB_DES
 	imply CRYPTO_CTR
@@ -1430,6 +1452,7 @@ config CRYPTO_CHACHA20
 config CRYPTO_CHACHA20_X86_64
 	tristate "ChaCha stream cipher algorithms (x86_64/SSSE3/AVX2/AVX-512VL)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_LIB_CHACHA_GENERIC
 	select CRYPTO_ARCH_HAVE_LIB_CHACHA
@@ -1473,6 +1496,7 @@ config CRYPTO_SERPENT
 config CRYPTO_SERPENT_SSE2_X86_64
 	tristate "Serpent cipher algorithm (x86_64/SSE2)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_SERPENT
 	select CRYPTO_SIMD
@@ -1492,6 +1516,7 @@ config CRYPTO_SERPENT_SSE2_X86_64
 config CRYPTO_SERPENT_SSE2_586
 	tristate "Serpent cipher algorithm (i586/SSE2)"
 	depends on X86 && !64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_SERPENT
 	select CRYPTO_SIMD
@@ -1511,6 +1536,7 @@ config CRYPTO_SERPENT_SSE2_586
 config CRYPTO_SERPENT_AVX_X86_64
 	tristate "Serpent cipher algorithm (x86_64/AVX)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_SERPENT
 	select CRYPTO_SIMD
@@ -1531,6 +1557,7 @@ config CRYPTO_SERPENT_AVX_X86_64
 config CRYPTO_SERPENT_AVX2_X86_64
 	tristate "Serpent cipher algorithm (x86_64/AVX2)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SERPENT_AVX_X86_64
 	help
 	  Serpent cipher algorithm, by Anderson, Biham & Knudsen.
@@ -1672,6 +1699,7 @@ config CRYPTO_TWOFISH_586
 config CRYPTO_TWOFISH_X86_64
 	tristate "Twofish cipher algorithm (x86_64)"
 	depends on (X86 || UML_X86) && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_ALGAPI
 	select CRYPTO_TWOFISH_COMMON
 	imply CRYPTO_CTR
@@ -1689,6 +1717,7 @@ config CRYPTO_TWOFISH_X86_64
 config CRYPTO_TWOFISH_X86_64_3WAY
 	tristate "Twofish cipher algorithm (x86_64, 3-way parallel)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_TWOFISH_COMMON
 	select CRYPTO_TWOFISH_X86_64
@@ -1709,6 +1738,7 @@ config CRYPTO_TWOFISH_X86_64_3WAY
 config CRYPTO_TWOFISH_AVX_X86_64
 	tristate "Twofish cipher algorithm (x86_64/AVX)"
 	depends on X86 && 64BIT
+	depends on !KMSAN # avoid false positives from assembly
 	select CRYPTO_SKCIPHER
 	select CRYPTO_SIMD
 	select CRYPTO_TWOFISH_COMMON
diff --git a/drivers/net/Kconfig b/drivers/net/Kconfig
index 6cccc3dc00bcf..d09dabc607a69 100644
--- a/drivers/net/Kconfig
+++ b/drivers/net/Kconfig
@@ -76,6 +76,7 @@ config WIREGUARD
 	tristate "WireGuard secure network tunnel"
 	depends on NET && INET
 	depends on IPV6 || !IPV6
+	depends on !KMSAN # KMSAN doesn't support the crypto configs below
 	select NET_UDP_TUNNEL
 	select DST_CACHE
 	select CRYPTO
