diff --git a/include/qemu/bitops.h b/include/qemu/bitops.h
index cb3526d1f4..2c0a2fe751 100644
--- a/include/qemu/bitops.h
+++ b/include/qemu/bitops.h
@@ -67,6 +67,19 @@ static inline void clear_bit(long nr, unsigned long *addr)
     *p &= ~mask;
 }
 
+/**
+ * clear_bit_atomic - Clears a bit in memory atomically
+ * @nr: Bit to clear
+ * @addr: Address to start counting from
+ */
+static inline void clear_bit_atomic(long nr, unsigned long *addr)
+{
+    unsigned long mask = BIT_MASK(nr);
+    unsigned long *p = addr + BIT_WORD(nr);
+
+    return qatomic_and(p, ~mask);
+}
+
 /**
  * change_bit - Toggle a bit in memory
  * @nr: Bit to change
diff --git a/migration/file.c b/migration/file.c
index 2f8b626b27..d949a941d0 100644
--- a/migration/file.c
+++ b/migration/file.c
@@ -150,3 +150,57 @@ void file_start_incoming_migration(FileMigrationArgs *file_args, Error **errp)
         }
     } while (++i < channels);
 }
+
+int file_write_ramblock_iov(QIOChannel *ioc, const struct iovec *iov,
+                            int niov, RAMBlock *block, Error **errp)
+{
+    ssize_t ret = -1;
+    int i, slice_idx, slice_num;
+    uintptr_t base, next, offset;
+    size_t len;
+
+    slice_idx = 0;
+    slice_num = 1;
+
+    /*
+     * If the iov array doesn't have contiguous elements, we need to
+     * split it in slices because we only have one file offset for the
+     * whole iov. Do this here so callers don't need to break the iov
+     * array themselves.
+     */
+    for (i = 0; i < niov; i++, slice_num++) {
+        base = (uintptr_t) iov[i].iov_base;
+
+        if (i != niov - 1) {
+            len = iov[i].iov_len;
+            next = (uintptr_t) iov[i + 1].iov_base;
+
+            if (base + len == next) {
+                continue;
+            }
+        }
+
+        /*
+         * Use the offset of the first element of the segment that
+         * we're sending.
+         */
+        offset = (uintptr_t) iov[slice_idx].iov_base - (uintptr_t) block->host;
+        if (offset >= block->used_length) {
+            error_setg(errp, "offset " RAM_ADDR_FMT
+                       "outside of ramblock %s range", offset, block->idstr);
+            ret = -1;
+            break;
+        }
+
+        ret = qio_channel_pwritev(ioc, &iov[slice_idx], slice_num,
+                                  block->pages_offset + offset, errp);
+        if (ret < 0) {
+            break;
+        }
+
+        slice_idx += slice_num;
+        slice_num = 0;
+    }
+
+    return (ret < 0) ? ret : 0;
+}
diff --git a/migration/file.h b/migration/file.h
index 4577f9efdd..01a338cac7 100644
--- a/migration/file.h
+++ b/migration/file.h
@@ -19,4 +19,6 @@ void file_start_outgoing_migration(MigrationState *s,
 int file_parse_offset(char *filespec, uint64_t *offsetp, Error **errp);
 void file_cleanup_outgoing_migration(void);
 bool file_send_channel_create(gpointer opaque, Error **errp);
+int file_write_ramblock_iov(QIOChannel *ioc, const struct iovec *iov,
+                            int niov, RAMBlock *block, Error **errp);
 #endif
diff --git a/migration/migration.c b/migration/migration.c
index ff3872468f..957d2890b7 100644
--- a/migration/migration.c
+++ b/migration/migration.c
@@ -139,12 +139,14 @@ static bool transport_supports_multi_channels(MigrationAddress *addr)
     if (addr->transport == MIGRATION_ADDRESS_TYPE_SOCKET) {
         SocketAddress *saddr = &addr->u.socket;
 
-        return saddr->type == SOCKET_ADDRESS_TYPE_INET ||
-               saddr->type == SOCKET_ADDRESS_TYPE_UNIX ||
-               saddr->type == SOCKET_ADDRESS_TYPE_VSOCK;
+        return (saddr->type == SOCKET_ADDRESS_TYPE_INET ||
+                saddr->type == SOCKET_ADDRESS_TYPE_UNIX ||
+                saddr->type == SOCKET_ADDRESS_TYPE_VSOCK);
+    } else if (addr->transport == MIGRATION_ADDRESS_TYPE_FILE) {
+        return migrate_mapped_ram();
+    } else {
+        return false;
     }
-
-    return false;
 }
 
 static bool migration_needs_seekable_channel(void)
@@ -1988,6 +1990,11 @@ static bool migrate_prepare(MigrationState *s, bool blk, bool blk_inc,
             error_setg(errp, "Cannot use TLS with mapped-ram");
             return false;
         }
+
+        if (migrate_multifd_compression()) {
+            error_setg(errp, "Cannot use compression with mapped-ram");
+            return false;
+        }
     }
 
     if (migrate_mode_is_cpr(s)) {
diff --git a/migration/multifd.c b/migration/multifd.c
index ea08f1aa9e..8118145428 100644
--- a/migration/multifd.c
+++ b/migration/multifd.c
@@ -108,6 +108,17 @@ void multifd_send_channel_created(void)
     qemu_sem_post(&multifd_send_state->channels_created);
 }
 
+static void multifd_set_file_bitmap(MultiFDSendParams *p)
+{
+    MultiFDPages_t *pages = p->pages;
+
+    assert(pages->block);
+
+    for (int i = 0; i < p->pages->num; i++) {
+        ramblock_set_file_bmap_atomic(pages->block, pages->offset[i]);
+    }
+}
+
 /* Multifd without compression */
 
 /**
@@ -169,6 +180,8 @@ static int nocomp_send_prepare(MultiFDSendParams *p, Error **errp)
 
     if (!multifd_use_packets()) {
         multifd_send_prepare_iovs(p);
+        multifd_set_file_bitmap(p);
+
         return 0;
     }
 
@@ -867,8 +880,15 @@ static void *multifd_send_thread(void *opaque)
                 break;
             }
 
-            ret = qio_channel_writev_full_all(p->c, p->iov, p->iovs_num, NULL,
-                                              0, p->write_flags, &local_err);
+            if (migrate_mapped_ram()) {
+                ret = file_write_ramblock_iov(p->c, p->iov, p->iovs_num,
+                                              p->pages->block, &local_err);
+            } else {
+                ret = qio_channel_writev_full_all(p->c, p->iov, p->iovs_num,
+                                                  NULL, 0, p->write_flags,
+                                                  &local_err);
+            }
+
             if (ret != 0) {
                 break;
             }
diff --git a/migration/options.c b/migration/options.c
index c6edbe4f3e..b6f39c57d8 100644
--- a/migration/options.c
+++ b/migration/options.c
@@ -654,12 +654,6 @@ bool migrate_caps_check(bool *old_caps, bool *new_caps, Error **errp)
     }
 
     if (new_caps[MIGRATION_CAPABILITY_MAPPED_RAM]) {
-        if (new_caps[MIGRATION_CAPABILITY_MULTIFD]) {
-            error_setg(errp,
-                       "Mapped-ram migration is incompatible with multifd");
-            return false;
-        }
-
         if (new_caps[MIGRATION_CAPABILITY_XBZRLE]) {
             error_setg(errp,
                        "Mapped-ram migration is incompatible with xbzrle");
@@ -1252,6 +1246,13 @@ bool migrate_params_check(MigrationParameters *params, Error **errp)
     }
 #endif
 
+    if (migrate_mapped_ram() &&
+        (migrate_multifd_compression() || migrate_tls())) {
+        error_setg(errp,
+                   "Mapped-ram only available for non-compressed non-TLS multifd migration");
+        return false;
+    }
+
     if (params->has_x_vcpu_dirty_limit_period &&
         (params->x_vcpu_dirty_limit_period < 1 ||
          params->x_vcpu_dirty_limit_period > 1000)) {
diff --git a/migration/ram.c b/migration/ram.c
index 329153d97d..87cb73fd76 100644
--- a/migration/ram.c
+++ b/migration/ram.c
@@ -1148,7 +1148,7 @@ static int save_zero_page(RAMState *rs, PageSearchStatus *pss,
 
     if (migrate_mapped_ram()) {
         /* zero pages are not transferred with mapped-ram */
-        clear_bit(offset >> TARGET_PAGE_BITS, pss->block->file_bmap);
+        clear_bit_atomic(offset >> TARGET_PAGE_BITS, pss->block->file_bmap);
         return 1;
     }
 
@@ -2445,8 +2445,6 @@ static void ram_save_cleanup(void *opaque)
         block->clear_bmap = NULL;
         g_free(block->bmap);
         block->bmap = NULL;
-        g_free(block->file_bmap);
-        block->file_bmap = NULL;
     }
 
     xbzrle_cleanup();
@@ -3135,9 +3133,22 @@ static void ram_save_file_bmap(QEMUFile *f)
         qemu_put_buffer_at(f, (uint8_t *)block->file_bmap, bitmap_size,
                            block->bitmap_offset);
         ram_transferred_add(bitmap_size);
+
+        /*
+         * Free the bitmap here to catch any synchronization issues
+         * with multifd channels. No channels should be sending pages
+         * after we've written the bitmap to file.
+         */
+        g_free(block->file_bmap);
+        block->file_bmap = NULL;
     }
 }
 
+void ramblock_set_file_bmap_atomic(RAMBlock *block, ram_addr_t offset)
+{
+    set_bit_atomic(offset >> TARGET_PAGE_BITS, block->file_bmap);
+}
+
 /**
  * ram_save_iterate: iterative stage for migration
  *
diff --git a/migration/ram.h b/migration/ram.h
index 9b937a446b..b9ac0da587 100644
--- a/migration/ram.h
+++ b/migration/ram.h
@@ -75,6 +75,7 @@ bool ram_dirty_bitmap_reload(MigrationState *s, RAMBlock *rb, Error **errp);
 bool ramblock_page_is_discarded(RAMBlock *rb, ram_addr_t start);
 void postcopy_preempt_shutdown_file(MigrationState *s);
 void *postcopy_preempt_thread(void *opaque);
+void ramblock_set_file_bmap_atomic(RAMBlock *block, ram_addr_t offset);
 
 /* ram cache */
 int colo_init_ram_cache(void);
